BOTTOM LINE GPA and MPA are distinct necrotizing small-size vessel anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) with overlapping features. GPA classically involves the upper respiratory tract (including destructive sinusitis), lungs…
BOTTOM LINE EGPA vasculitis (formerly “Churg-Strauss Syndrome”) is a small/medium vessel necrotizing granulomatous systemic vasculitis characterized by asthma and chronic rhinosinusitis with blood and tissue eosinophilia; systemic symptoms may include…
BOTTOM LINE Immune complex mediated vasculitis is a group of small vessel vasculitis caused by deposition of immunoglobulin and/or complement on vessel walls. Common features include purpuric skin rash, neuropathy,…
BOTTOM LINE Mixed cryoglobulinemia syndrome is caused by the precipitation of serum immunoglobulins at temperatures <37°C and manifests as immune complex-mediated small-medium vessel vasculitis commonly associated with chronic hepatitis C,…