• Overview of Autoinflammatory Diseases

    BOTTOM LINE Autoinflammatory Disease generally refers to a broad spectrum of diseases related to inappropriate antigen-independent activation of the innate immune system. Autoinflammatory diseases are often (but not always) characterized…

  • Still’s Disease

    BOTTOM LINE Still’s disease encompasses systemic Juvenile Idiopathic Arthritis (sJIA) and Adult-onset Still’s Disease (AOSD). Still’s Disease results from dysfunction of the adaptive and innate immune system. Genetically, Still’s Disease…