• Overview of Autoinflammatory Diseases

    BOTTOM LINE CONTINUUM OF AUTOINFLAMMATORY AND AUTOIMMUNE DISEASES Innate immunity Adaptive immunity Specificity hard-wired recognition of molecular patterns shared by pathogens and damaged host cells learned recognition of microbial and…

  • Still’s Disease

    BOTTOM LINE Still’s disease encompasses systemic Juvenile Idiopathic Arthritis (sJIA) and Adult-onset Still’s Disease (AOSD). Still’s Disease results from dysfunction of the adaptive and innate immune system. Genetically, Still’s Disease…